MR study finds no causal link between age at menarche or age at menopause and Alzheimer’s risk

Aging-US published “The role of age at menarche and age at menopause in Alzheimer’s disease: evidence from a bidirectional mendelian randomization study” which reported that the association between endogenous estrogen exposure and Alzheimer’s disease remains inconclusive in previous observational studies, and few Mendelian randomization studies have focused on their causality thus far.

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